Microbiological Profile of Peritoneal Dialysis-Related Peritonitis at Dr. Hasan Sadikin Hospital, Bandung

  • Dania Artriana Division of Nephrology & Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia https://orcid.org/0009-0003-5421-9219
  • Llik Sukesi Division of Nephrology & Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia https://orcid.org/0000-0001-6087-6782
  • Rizky Andhika Division of Nephrology & Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia https://orcid.org/0000-0001-9599-3911
Keywords: CAPD, Microbiological Profile, Peritonitis

Abstract

Background: Peritonitis is a frequent complication in patients undergoing peritoneal dialysis. To provide appropriate therapy, identification of the pathogen that causes peritonitis is required.

Objective: This study aims to understand the microbiological profile of CAPD peritonitis in hospitalized patients at Dr. Hasan Sadikin Hospital, Bandung.

Methods: This was a descriptive retrospective study using secondary data of peritonitis patients undergoing CAPD in 2020-2023. A total sampling technique was used, where all cases that met the inclusion criteria were included. The criteria were patients aged ≥ 18 years with CAPD peritonitis, having complete medical record data, and CAPD fluid culture results. In addition, the data were analyzed using SPSS software.

Results: A total of 67 peritonitis patients undergoing CAPD were included, with 36 (53.7%) having monomicrobial infections. In addition, 7.5% had polymicrobial infection and 38% had culture-negative. Gram-negative bacteria were the most common microbe found in 18 cases, and most patients recovered from peritonitis (86.6%), followed by catheter removal (9%), and death (4.5%). Gram-negative predominance contrasts with Ozdemir et al.’s findings, possibly due to regional antibiotic practices.

Conclusion: Empirical antibiotic treatment and culture results helped in providing effective management. Adhering to ISPD guidelines and improving sampling techniques could improve microbiological diagnosis and patient outcomes.

Downloads

Download data is not yet available.

References

1. Bikbov B, Purcell CA, Levey AS, Smith M, Abdoli A, Abebe M, et al. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020 Feb;395(10225):709–33. doi:10.1016/s0140-6736(20)30045-3
2. Perera S, Palasuntheram C. Microbiological aspects of peritonitis in patients undergoing chronic peritoneal dialysis at the dialysis unit of Sri Jayawardenapura General Hospital. Ceylon Med J. 2001;46(2):45–7. doi:10.4038/cmj.v46i2.6490
3. Ghali JR, Bannister KM, Brown FG, Rosman JB, Wiggins KJ, Johnson DW, et al. Microbiology and outcomes of peritonitis in Australian peritoneal dialysis patients. Perit Dial Int. 2011;31(6):651–62. doi:10.3747/pdi.2010.00131
4. Wang HH, Huang CH, Kuo MC, Lin SY, Hsu CH, Lee CY, et al. Microbiology of peritoneal dialysis-related infection and factors of refractory peritoneal dialysis related peritonitis: A ten-year single-center study in Taiwan. J Microbiol Immunol Infect. 2019 Oct;52(5):752–9. doi:10.1016/j.jmii.2018.10.013
5. Abraham G, Gupta A, Prasad KN, Rohit A, Bhalla AK, Billa V, et al. Microbiology, clinical spectrum and outcome of peritonitis in patients undergoing peritoneal dialysis in India: Results from a multicentric, observational study. Indian J Med Microbiol. 2017;35(4):491–8. doi:10.4103/ijmm.ijmm_17_392
6. Li PKT, Chow KM, Cho Y, Fan S, Figueiredo AE, Harris T, et al. ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment. Perit Dial Int. 2022;42(2):110–53. doi:10.1177/08968608221080586
7. Solin RSC, Kumalawati J, Yusra Y, Indrasari ND. Microbial profile, peritoneal fluid white blood cell count, and outcome of peritoneal dialysis-related peritonitis at Indonesian Tertiary Hospital. J Glob Infect Dis. 2023;15(3):108–12. doi:10.4103/jgid.jgid_16_23
8. Özdemir A, Koçak SY. Peritoneal dialysis-related peritonitis: Microbiological profile and outcome. Med J Bakirkoy. 2022;18(1):25–30. doi:10.4274/bmj.galenos.2022.2021.12-6
9. Hu S, Ming P, Qureshi AR, Lindholm B, Bo Y, Yang H, et al. Peritonitis: episode sequence, microbiological variation, risk factors and clinical outcomes in a North China peritoneal dialysis center. Kidney Blood Press Res. 2018;43(5):1573–84. doi:10.1159/000494443
10. Phui VE, Tan CHH, Chen CK, Lai KH, Chew KF, Chua HH, et al. Causative organisms and outcomes of peritoneal dialysis-related peritonitis in Sarawak General Hospital, Kuching, Malaysia: a 3-year analysis. Ren Replace Ther. 2017;3:1–7. doi:10.1186/s41100-017-0117-8
11. Srivastava AK, Ghosh I, Sonawane S. Clinical profile and microbiological spectrum of patients with continuous ambatory peritoneal dialysis-associated peritonitis at a tertiary care center. Med J Armed Forces India. 2023;79(Suppl 1):S175--S180. doi:10.1016/j.mjafi.2022.05.001
Published
2025-08-24
How to Cite
1.
Artriana D, Sukesi L, Andhika R. Microbiological Profile of Peritoneal Dialysis-Related Peritonitis at Dr. Hasan Sadikin Hospital, Bandung. inakidney [Internet]. 24Aug.2025 [cited 5Mar.2026];2(2):73-0. Available from: https://inakidneyhypertension.co.id/index.php/inakidney/article/view/191
Section
Original Articles