Association Between Intradialysis Hypotension and Interdialytic Weight Gain in Deceased Hemodialysis Patients at Banyumas Regional General Hospital

Gigih Rahmandanu Poernomo; Dwi Lestari Partiningrum; Lestariningsih Lestariningsih; Ayudyah Nurani; Arwedi Arwanto; Shofa Chasani; Haidar Alatas

doi:10.32867/inakidney.v2i1.178

Gigih Rahmandanu Poernomo Trainee in Nephrology and Hypertension. Division of Nephrology and Hypertension, Department of Internal Medicine. Faculty of Medicine. Universitas Diponegoro/Kariadi Hospital, Semarang, Indonesia https://orcid.org/0009-0003-1461-7124
Dwi Lestari Partiningrum Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro/Kariadi Hospital, Semarang, Indonesia https://orcid.org/0000-0001-8101-1825
Lestariningsih Lestariningsih Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro/Kariadi Hospital, Semarang, Indonesia https://orcid.org/0000-0003-0619-7708
Ayudyah Nurani Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro/Kariadi Hospital, Semarang, Indonesia https://orcid.org/0000-0001-9651-1961
Arwedi Arwanto Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro/Kariadi Hospital, Semarang, Indonesia
Shofa Chasani Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Diponegoro/Kariadi Hospital, Semarang, Indonesia https://orcid.org/0000-0003-0161-8155
Haidar Alatas Department of Internal Medicine, Banyumas Regional General Hospital, Banyumas, Indonesia https://orcid.org/0000-0002-5445-349X

DOI: https://doi.org/10.32867/inakidney.v2i1.178

Keywords: Chronic Kidney Disease, Hemodialysis, Interdialytic Weight Gain, Intradialytic Hypotension, Diabetes Mellitus

Abstract

Background: Intradialytic hypotension (IDH) occurs in 5-40 percent of chronic kidney disease (CKD) with hemodialysis patients, it is associated with increased cardiovascular events and mortality. High Interdialytic Weight Gain (IDWG) requires higher ultrafiltration, increases the incidence of IDH, associated with a worse prognosis, patients with a history of diabetes are at higher risk.

Objective: This study aimed to assess the association between IDWG and the occurrence of IDH in deceased patients undergoing hemodialysis, with a particular focus on the differences between diabetic and non-diabetic patients

Methods: A retrospective study was conducted for one year at Banyumas Regional General Hospital, involving deceased hemodialysis patients. IDWG was calculated as the average of the last three hemodialysis sessions. Patients were further categorized based on their history of diabetes.

Results: Among 37 deceased hemodialysis patients, 56.8% experienced IDH, including 50% of those with diabetes mellitus. IDWG was normally distributed (p = 0.283) and showed a weak but statistically significant correlation with IDH (r = 0.333, p = 0.044). Logistic regression indicated that each 1% increase in IDWG was associated with an 8% increase in the predicted probability of IDH. Diabetic status did not significantly modify this association (p = 0.772).

Conclusion: Higher IDWG was associated with increased incidence of IDH in deceased hemodialysis patients, independent of diabetic status.

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