Characteristics and Clinical Outcomes of COVID-19 in ESRD Patients Undergoing Hemodialysis in Ngudi Waluyo Wlingi General Hospital in 2020-2022

  • Fajar Hadi Wijayanto Department of Internal Medicine, Ngudi Waluyo Wlingi General Hospital, Blitar, Indonesia https://orcid.org/0009-0005-6570-1013
  • Aleyda Zahratunany Insanitaqwa Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia https://orcid.org/0009-0000-1646-5644
  • Syarifiyana Mawaddah Ngudi Waluyo Wlingi General Hospital, Blitar, Indonesia
Keywords: Chronic Kidney Disease, COVID-19, Hemodialysis, Renal Insufficiency, Renal Dialysis

Abstract

Background: The coronavirus disease (COVID-19) pandemic is a major threat to global health care. Comorbidities, including end-stage renal disease (ESRD), are related to an increased risk of severe infection and mortality.

Objective: To assess determinants related to the clinical outcomes of COVID-19 in ESRD patients undergoing hemodialysis in Ngudi Waluyo Wlingi General Hospital in 2020-2022.

Methods: This study included ESRD patients undergoing maintenance hemodialysis who were hospitalized at Ngudi Waluyo Wlingi General Hospital due to COVID-19 from May 2020 to February 2022. Clinical characteristics were investigated in relation to the severity and survival status.

Results: A total of 26 patients (46.15% male) with a mean age of 52.27±13.65 years met the inclusion criteria. Of these, 42.3% had a mild infection, 23% had a moderate infection, 30.77% had a severe infection, and 3.8% had a critical infection. The mortality rate was 23.08%, with a mean length of stay of 15.19±7 days. Age, oxygen saturation, respiratory rate upon admission, lymphocyte and neutrophil levels, and neutrophil-to-lymphocyte ratio were significantly associated with COVID-19 severity. Length of stay was statistically influenced by respiratory rate upon admission. The mortality rate was correlated with the dialysis vintage, levels of hemoglobin, leukocytes, platelets, neutrophils, neutrophil-to-lymphocyte ratio, serum urea, serum creatinine, eGFR, and length of stay.

Conclusion: COVID-19 in ESRD patients undergoing hemodialysis were more likely to have a poor prognosis. Identifying determinants is crucial for reducing morbidity and mortality.

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Published
2024-12-24
How to Cite
1.
Wijayanto F, Insanitaqwa A, Mawaddah S. Characteristics and Clinical Outcomes of COVID-19 in ESRD Patients Undergoing Hemodialysis in Ngudi Waluyo Wlingi General Hospital in 2020-2022. inakidney [Internet]. 24Dec.2024 [cited 7Feb.2025];1(3):26-8. Available from: https://inakidneyhypertension.co.id/index.php/inakidney/article/view/156